Top 100 Biotechnology Companies

The following is a list of the top 100 companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies.

Rank 2006	Company	Country	Revenue in 2006 (USD millions)	R&D in 2006 (USD millions)	Net income/ (loss) in 2006 (USD millions)	Employees in 2006
1	Amgen	USA	14,268.0	3,366.0	2,950.0	20,100
2	Genentech	USA	9,284.0	1,773.0	2,113.0	10,533
3	Genzyme	USA	3,187.0	650.0	-16.8	9,000+
4	UCB	Belgium	3,169.6	772.6	461.1	8,477
5	Gilead Sciences	USA	3,026.1	383.9	-1,190.0	7,575
6	Serono	Switzerland	2,804.9	560.5	735.4	4,775
7	Biogen Idec	USA	2,683.0	718.4	217.5	3,750
8	CSL	Australia	2,148.3	119.1	86.8	2,895
9	Cephalon	USA	1,764.1	403.4	144.8	2,515
10	MedImmune	USA	1,276.8	448.9	48.7	2,359
11	Celgene	USA	898.9	258.6	69.0	1,864
12	Abraxis BioScience	USA	765.5	96.9	-46.9	1,734
13	Actelion	Switzerland	754.6	169.0	192.4	1,550
14	ImClone Systems	USA	677.8	112.1	370.7	1,287
15	Élan	Ireland	560.4	215.9	-267.3	1,252
16	Amylin Pharmaceuticals	USA	510.9	222.1	-218.9	1,100
17	Millennium Pharmaceuticals	USA	486.8	318.2	-44.0	1,073
18	PDL BioPharma	USA	414.8	260.7	-130.0	993
19	OSI Pharmaceuticals	USA	375.7	176.7	-582.2	962
20	MGI Pharma	USA	342.8	100.1	-40.2	947
21	Pharmion	USA	238.6	70.1	-91.0	793
22	Nektar Therapeutics	USA	217.7	149.4	-154.8	770
23	Vertex Pharmaceuticals	USA	216.4	371.7	-206.9	760
24	Biocon	India	200.3	30.5	43.5	1838
25	Cubist Pharmaceuticals	USA	194.7	57.4	-0.4	746
26	Enzon Pharmaceuticals	USA	185.7	43.5	21.3	722
27	QLT	Canada	175.1	56.4	-101.6	653
28	ViroPharma	USA	167.2	19.2	66.7	651
29	Alkermes	USA	166.6	89.1	3.8	617
30	Crucell	Netherlands	165.3	84.9	-110.0	611
31	United Therapeutics	USA	159.6	57.6	74.0	585
32	LifeCell	USA	141.7	16.5	20.5	573
33	Ligand Pharmaceuticals	USA	141.0	41.9	-31.7	540
34	Myriad Genetics	USA	114.3	83.8	-38.2	511
35	Exelixis	USA	98.7	185.5	-101.5	500
36	Cangene	Canada	96.8	22.1	11.6	498
37	InterMune	USA	90.8	103.8	-107.2	492
38	Nabi Biopharmaceuticals	USA	89.9	37.6	-58.7	487
39	BioMarin Pharmaceutical	USA	84.2	66.7	-28.5	417
40	Lexicon Pharmaceuticals	USA	72.8	106.7	-54.3	410
41	Progenics Pharmaceuticals	USA	69.9	61.7	-21.6	410
42	Innogenetics	Belgium	67.5	32.1	-31.5	371
43	Idenix Pharmaceuticals	USA	67.4	96.1	-75.1	359
44	MorphoSys	Germany	66.6	21.9	7.6	336
45	Omrix Biopharmaceuticals	USA	63.8	3.4	23.1	335
46	Regeneron Pharmaceuticals	USA	63.4	137.1	-102.3	323
47	Acambis	UK	57.0	68.2	-30.4	285
48	Tanox	USA	56.1	53.4	-2.6	285
49	ViaCell	USA	54.4	14.0	-21.0	282
50	Indevus Pharmaceuticals	USA	50.5	43.2	-50.6	279
51	Medarex	USA	48.6	194.5	-181.7	277
52	NPS Pharmaceuticals	USA	48.5	68.4	-112.7	276
53	Monogram Biosciences	USA	48.0	19.0	-38.7	274
54	Oscient Pharmaceuticals	USA	46.2	12.4	-78.5	267
55	Array BioPharma	USA	45.0	33.4	-39.6	263
56	AEterna Zentaris	Canada	41.4	28.7	33.4	260
57	IsoTis	Switzerland	40.7	7.7	-18.5	255
58	Enzo Biochem	USA	39.8	7.9	-15.7	255
59	CuraGen	USA	39.6	58.5	-59.8	254
60	Neurocrine Biosciences	USA	39.2	97.7	-107.2	254
61	MediGene	Germany	38.4	26.7	-8.7	248
62	Life Therapeutics	Australia	37.6	0.1	-31.2	245
63	Inspire Pharmaceuticals	USA	37.1	42.5	-42.1	238
64	CV Therapeutics	USA	36.8	135.3	-274.3	233
65	Cerus	USA	35.6	29.5	-4.8	208
66	SciClone Pharmaceuticals	USA	32.7	14.1	0.7	197
67	ImmunoGen	USA	32.1	40.9	-17.8	197
68	Protherics	UK	30.9	11.8	-16.5	196
69	Arena Pharmaceuticals	USA	30.6	103.4	-88.3	195
70	Vernalis	UK	30.1	71.7	-78.2	192
71	Bavarian Nordic	Denmark	29.5	19.9	-27.1	191
72	Xoma	USA	29.5	52.1	-51.8	189
73	GPC Biotech	Germany	28.5	81.3	-80.4	180
74	Micromet	USA	27.6	28.3	0.0	171
75	Targacept	USA	27.5	21.8	-1.2	170
76	Carrington Laboratories	USA	27.4	5.8	-7.6	166
77	Acorda Therapeutics	USA	27.4	12.1	-60.0	158
78	Anika Therapeutics	USA	26.8	3.6	4.6	156
79	Human Genome Sciences	USA	25.8	209.2	-251.2	151
80	Dusa Pharmaceuticals	USA	25.6	6.2	-31.3	150
81	ZymoGenetics	USA	25.4	128.5	-130.0	150
82	Maxygen	USA	25.0	49.1	-16.5	147
83	Isis Pharmaceuticals	USA	24.5	80.6	-45.9	133
84	Genmab	Denmark	23.9	90.6	-77.4	128
85	Bioniche Life Sciences	Canada	23.9	11.6	-1.0	126
86	Vitrolife	Sweden	23.2	3.3	2.1	124
87	Coley Pharmaceutical Group	USA	20.2	40.9	-29.4	122
88	Palatin Technologies	USA	19.7	41.0	-29.0	116
89	Encysive Pharmaceuticals	USA	19.0	64.4	-109.3	109
90	GenVec	USA	18.9	29.6	-19.3	95
91	Medivir Group	Sweden	18.8	39.7	-29.7	88
92	Peptech	Australia	18.7	4.6	3.8	85
93	Ambrilia Biopharma	Canada	17.4	8.3	-2.1	85
94	Cytogen	USA	17.3	7.3	-15.1	85
95	Replidyne	USA	16.0	38.3	-34.6	79
96	Sinovac Biotech	China	15.4	0.3	-0.7	67
97	Trimeris	USA	15.2	18.3	7.4	64
98	Avanir Pharmaceuticals	USA	15.2	29.2	-62.6	64
99	Adolor	USA	15.1	56.7	-69.7	51
100	Curis	USA	14.9	14.6	-8.8	46

Source: Top 100 biotechnology companies, MedAdNews, June 2007